Charles W. Mayser devoted 45 years of his life to coaching and athletic administration, the last 24 of these at Franklin and Marshall College. It was as a wrestling coach that Mayser achieved his greatest acclaim. After successfully coaching football at F&M in 1913 and 1914, Mayser went to Iowa State, where he was the Cyclones football coach and started their nationally renowned wrestling program. His wrestling record there was 84-3-1and it was at Iowa State that he acquired his nickname of "Uncle Charley." Returning to F&M in 1924 as the Director of Physical Education, Mayser initiated wrestling and coached the sport until his retirement in 1946.
Under his guidance, the Blue & White had one of its greatest periods of sports prosperity, with the wrestling teams leading the way. Mayser-coached teams compiled a 145-20-3 record between 1924 and 1944 when they regularly challenged the wrestling greats across the country. F&M hosted both AAU and NCAA national meets at the Lancaster Armory. In 1939, F&M finished fourth in the nationals behind Oklahoma, Lehigh, and Illinois. Mayser's contribution to the wrestling world was recognized when he was elected to membership in the Helm's Wrestling Hall of Fame.
In addition to his professional pursuits, Uncle Charley also found plenty of time to work with youth in the community and to give his "magic shows" for children in the hospital and others who needed some brightness in their lives. The Mayser Physical Education Center was named in honor of Mayser"s contribution, not only to F&M, but to the entire Lancaster community.